University of Manchester Logo basement membraneBASE bmBASE
HMCN1 TagInt
Entry ID: BMB30730
Tag — Tagged gene or ortholog (via endogenous labelling). See the Protein Localisation tab.
Int — Basement membrane interaction. See the BM Ligands tab.

Link to hereGene

Species
Human (Homo sapiens)
Gene Symbol
HMCN1
Gene Size (Bases)
456559

Link to hereProtein

Protein Name
Hemicentin 1
Protein Classification
ECM glycoprotein
Protein Molecular Weight (kD)
613
Protein Domains
IPR000742:EGF-like domain, IPR003599:Immunoglobulin subtype domain, IPR007110:Immunoglobulin-like domain, IPR001881:EGF-like calcium-binding domain, IPR006605:G2 nidogen/fibulin G2F domain, IPR003598:Immunoglobulin subtype 2 domain
This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species
Caenorhabditis elegans — 1 ortholog(s) of HMCN1 Tag
Zebrafish (Danio rerio) — 1 ortholog(s) of HMCN1
Drosophila — 1 ortholog(s) of HMCN1
Mouse (Mus musculus) — 1 ortholog(s) of HMCN1

Link to hereProtein Localisation

Localisation Images (0)
Localisation Evidence (0)

Link to hereOther Information

Proteomics
BM Substrates (0)
This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.
BM Ligands (4)
Gene
FRAS1
FREM1
FREM2
FREM3
This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .
Associated Diseases (1)
Macular degeneration, age-related, 1 HPO
This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References
Entrez/83872 UniProtKB/Q96RW7
If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.