Mmp2 (Matrix metalloproteinase 2) in Drosophila - bmBASE - A resource for basement membrane research

IPR006026:Peptidase, metallopeptidase domain, IPR000585:Hemopexin-like domain, IPR001818:Peptidase M10, metallopeptidase domain, IPR002477:Peptidoglycan binding-like domain, IPR033739:Peptidase M10A, catalytic domain, IPR024079:Metallopeptidase, catalytic domain superfamily domain, IPR036375:hemopexin-like domain superfamily domain, IPR018487:hemopexin-like repeats domain, IPR021190:peptidase M10A domain, IPR036365:PGBD-like superfamily domain

This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species

Caenorhabditis elegans — 6 ortholog(s) of Mmp2

Zebrafish (Danio rerio) — 1 ortholog(s) of Mmp2

Human (Homo sapiens) — 1 ortholog(s) of Mmp2

Mouse (Mus musculus) — 1 ortholog(s) of Mmp2

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (1)

Basement membrane damage by ROS- and JNK-mediated Mmp2 activation drives macrophage recruitment to overgrown tissue. PubMed

Found in: Drosophila

Reagents: Antibody was a gift from Kendal Broadie (PMID: 26603384)

Comment: Fig. 4

Link to hereOther Information

Proteomics

BM Substrates (3)

CtsB1, dg, SMC3

This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.

BM Ligands (8)

Gene
Mp
cathD
trol
Timp
Meltrin
kuz
if
mys

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

Associated Diseases (0)

This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References

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