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Timp EnzInt
Entry ID: BMB31025
Enz — Basement membrane protease. See the BM Substrates tab.
Int — Basement membrane interaction. See the BM Ligands tab.

Link to hereGene

Species
Drosophila
Gene Symbol
Timp
Gene Size (Bases)
9133

Link to hereProtein

Protein Name
Tissue inhibitor of metalloproteases
Protein Classification
ECM regulator
Protein Molecular Weight (kD)
24
Protein Domains
IPR001134:Netrin domain, IPR008993:Tissue inhibitor of metalloproteinases-like, OB-fold domain, IPR001820:protease inhibitor I35 (TIMP) domain, IPR027465:proteinase inhibitor I35b (TIMP), C-terminal domain
This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species
Caenorhabditis elegans — 2 ortholog(s) of Timp
Zebrafish (Danio rerio) — 3 ortholog(s) of Timp
Human (Homo sapiens) — 3 ortholog(s) of Timp
Mouse (Mus musculus) — 3 ortholog(s) of Timp

Link to hereProtein Localisation

Localisation Images (0)
Localisation Evidence (0)

Link to hereOther Information

Proteomics
BM Substrates (2)
Mmp1, Mmp2
This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.
BM Ligands (5)
Gene
Mmp1
Mmp2
Reck
kuz
Tace
This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .
Associated Diseases (0)
This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References
If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.