SLIT2 (Slit Guidance Ligand 2) in Human (Homo sapiens) - bmBASE - A resource for basement membrane research

IPR000742:EGF-like domain, IPR006207:Cystine knot, C-terminal domain, IPR001881:EGF-like calcium-binding domain, IPR003645:Follistatin-like, N-terminal domain, IPR001791:Laminin G domain, IPR000483:Cysteine-rich flanking region, C-terminal domain, IPR000372:Leucine-rich repeat N-terminal domain

This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species

Caenorhabditis elegans — 1 ortholog(s) of SLIT2

Zebrafish (Danio rerio) — 1 ortholog(s) of SLIT2

Drosophila — 1 ortholog(s) of SLIT2

Mouse (Mus musculus) — 1 ortholog(s) of SLIT2

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (1)

Slit2 promotes tumor growth and invasion in chemically induced skin carcinogenesis. PubMed

Found in: Human (Homo sapiens)

Reagents: Anti-slit 2 (Abcam)

Comment: See Fig. 1

Link to hereOther Information

Proteomics

BM Substrates (0)

This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.

BM Ligands (7)

Gene
NTN1
SLIT1
SLIT3
ROBO1
ROBO3
ROBO4
ROBO2

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

Associated Diseases (0)

This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References

Entrez/9353 UniProtKB/O94813

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.