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SLIT1 Int
Entry ID: BMB30928
Int — Basement membrane interaction. See the BM Ligands tab.

Link to hereGene

Species
Human (Homo sapiens)
Gene Symbol
SLIT1
Gene Size (Bases)
187922

Link to hereProtein

Protein Name
Slit Guidance Ligand 1
Protein Classification
ECM glycoprotein
Protein Molecular Weight (kD)
168
Protein Domains
IPR000742:EGF-like domain, IPR006207:Cystine knot, C-terminal domain, IPR001881:EGF-like calcium-binding domain, IPR003645:Follistatin-like, N-terminal domain, IPR001791:Laminin G domain, IPR000483:Cysteine-rich flanking region, C-terminal domain, IPR000372:Leucine-rich repeat N-terminal domain
This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species
Caenorhabditis elegans — 1 ortholog(s) of SLIT1
Zebrafish (Danio rerio) — 2 ortholog(s) of SLIT1
Drosophila — 1 ortholog(s) of SLIT1
Mouse (Mus musculus) — 1 ortholog(s) of SLIT1

Link to hereProtein Localisation

Localisation Images (0)
Localisation Evidence (0)

Link to hereOther Information

Proteomics
BM Substrates (0)
This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.
BM Ligands (8)
Gene
COL4A5
NTN1
SLIT2
SLIT3
ROBO1
ROBO3
ROBO4
ROBO2
This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .
Associated Diseases (0)
This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References
Entrez/6585 UniProtKB/O75093
If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.