University of Manchester Logo basement membraneBASE bmBASE

DCC

Int — Basement membrane interaction. See Interactions.
Entry ID: BMB31107
Gene
Species Human (Homo sapiens)
Gene Symbol DCC
Gene Size (Bases) 1195732
Entrez 1630
Protein
Protein Name DCC Netrin 1 Receptor
Classification Receptor
Mol. Weight (kD) 158
UniProtKB P43146
Protein Domains Immunoglobulin domain subtype , Immunoglobulin-like domain , Immunoglobulin subtype 2 , Fibronectin type III , Neogenin, C-terminal + 4 more…
May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (0)
Localisation Evidence (0)

Link to hereInteractions

BM Substrates (0)
BM Ligands (11)
Gene
NTN1
NTN4
SLIT1
SLIT2
SLIT3
ROBO1
UNC5A
UNC5B
UNC5C
UNC5D
ROBO2
This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .
Interaction Network Images

Link to hereAssociated Diseases

Associated Diseases (3)
Esophageal cancer, somatic OMIM
Gaze palsy, familial horizontal, with progressive scoliosis 2, with impaired intellectual dev OMIM
Mirror movements 1 OMIM
This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereMultiomics

Proteomics

Link to hereOrthology

Orthologs by Species
Caenorhabditis elegans — 1 ortholog(s) of DCC
Zebrafish (Danio rerio) — 1 ortholog(s) of DCC
Drosophila — 1 ortholog(s) of DCC
Mouse (Mus musculus) — 1 ortholog(s) of DCC

Link to hereSee also

External References
Publication: A basement membrane discovery pipeline/sciadv.abn2265
If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.