Adamts1

Ab — Antibody evidence. See Protein Localisation. Int — Basement membrane interaction. See Interactions.

Entry ID: BMB30445

Protein Localisation

Associated Diseases

Gene

Species	Mouse (Mus musculus)
Gene Symbol	Adamts1
Gene Size (Bases)	9287
Entrez	11504

Protein

Protein Name	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 1
Classification	ECM regulator
Mol. Weight (kD)	106
UniProtKB	P97857
Protein Domains	ADAM, cysteine-rich domain , Peptidase M12B, ADAM/reprolysin , Peptidase M12B, propeptide , ADAMTS, cysteine-rich domain 2 , ADAMTS/ADAMTS-like, Spacer 1 , ADAMTS/ADAMTS-like , Thrombospondin type-1 (TSP1) repeat , Peptidase M12B, ADAM-TS1 , ADAMTS and ADAMTS-like + 7 more… May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (2)

Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1 PubMed

Found in: Mouse (Mus musculus)

Reagents: α-ADAMTS-1 GP12 (BIO-SOURCE)
Proteolytic cleavage of versican and involvement of ADAMTS-1 in VEGF-A/VPF-induced pathological angiogenesis. PubMed

Found in: Mouse (Mus musculus)

Reagents: α-ADAMTS-1 (Cedarlane Laboratories)

Link to hereInteractions

BM Substrates (0)

BM Ligands (1)

Gene
Fbln1

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

Interaction Network Images

Link to hereAssociated Diseases

Associated Diseases (0)

Link to hereMultiomics

Proteomics

proteinBASE/Mouse kidney proteomics

Link to hereOrthology

Orthologs by Species

Zebrafish (Danio rerio) — 1 ortholog(s) of Adamts1

Drosophila — 1 ortholog(s) of Adamts1

Human (Homo sapiens) — 1 ortholog(s) of Adamts1

Link to hereSee also

External References

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.