ADAMTS10 (ADAM Metallopeptidase With Thrombospondin Type 1 Motif 10) in Human (Homo sapiens) - bmBASE - A resource for basement membrane research

IPR001590:Peptidase M12B, ADAM/reprolysin domain, IPR002870:Peptidase M12B, propeptide domain, Peptidase M12B, propeptide:ADAM-TS Spacer 1 domain, IPR010909:PLAC domain, IPR041645:ADAM cysteine-rich domain 2 domain

This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species

Caenorhabditis elegans — 1 ortholog(s) of ADAMTS10 Tag

Zebrafish (Danio rerio) — 1 ortholog(s) of ADAMTS10

Mouse (Mus musculus) — 1 ortholog(s) of ADAMTS10

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (2)

ADAMTS10 protein interacts with fibrillin-1 and promotes its deposition in extracellular matrix of cultured fibroblasts. PubMed

Found in: Human (Homo sapiens)

Reagents: in-house ɑ-ADAMTS10 mAb (PMID: 21402694)

Comment: Figure 3
Human Protein Atlas HPA

Found in: Human (Homo sapiens)

Reagents: ɑ-ADAMTS10 pAb (Atlas Antibodies, HPA040223)

Comment: Skin localisation

Link to hereOther Information

Proteomics

BM Substrates (0)

This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.

BM Ligands (22)

Gene
ADAMTS1
ADAMTS2
ADAMTS3
ADAMTS4
ADAMTS5
ADAMTS6
ADAMTS7
ADAMTS8
ADAMTS9
ADAMTS13
ADAMTS14
ADAMTS15
ADAMTS16
ADAMTS17
ADAMTS18
ADAMTS19
ADAMTS20
FBN1
SPON1
SPON2
THBS1
THBS2

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

Associated Diseases (1)

Weill-Marchesani syndrome 1 OMIM

This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References

Entrez/81794 UniProtKB/Q9H324

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.