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ADAMTS2

Int — Basement membrane interaction. See BM Ligands.
Entry ID: BMB30449
Gene
Species Human (Homo sapiens)
Gene Symbol ADAMTS2
Gene Size (Bases) 234609
Entrez 9509
Protein
Protein Name ADAM Metallopeptidase With Thrombospondin Type 1 Motif 2
Classification ECM regulator
Mol. Weight (kD) 135
UniProtKB O95450
Protein Domains IPR001590, IPR002870, Peptidase M12B, propeptide, IPR010909, IPR041645
May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (0)
Localisation Evidence (1)

Link to hereOther Information

Proteomics
BM Substrates (9)
ADAMTS1, DCN, FBLN2, FN1, HSPG2, LOXL1, THBS1, VCAN, ADAM10
This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.
BM Ligands (26)
Gene
ADAMTS1
ADAMTS3
ADAMTS4
ADAMTS5
ADAMTS6
ADAMTS7
ADAMTS8
ADAMTS9
ADAMTS10
ADAMTS13
ADAMTS14
ADAMTS15
ADAMTS16
ADAMTS17
ADAMTS18
ADAMTS19
ADAMTS20
COL2A1
COL5A1
EFEMP2
SPON1
SPON2
THBS1
THBS2
COL5A2
COL5A3
This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .
Interaction Network Images
Associated Diseases (1)
Ehlers-danlos Syndrome, Type Vii, Autosomal Recessive OMIM
This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereOrthology

Orthologs by Species
Zebrafish (Danio rerio) — 1 ortholog(s) of ADAMTS2
Mouse (Mus musculus) — 1 ortholog(s) of ADAMTS2

Link to hereSee also

External References
Entrez/9509 UniProtKB/O95450 Publication: A basement membrane discovery pipeline/sciadv.abn2265
If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.