COL2A1

Int — Basement membrane interaction. See BM Ligands.

Entry ID: BMB30526

Protein Localisation

Other Information

Gene

Species	Human (Homo sapiens)
Gene Symbol	COL2A1
Gene Size (Bases)	33246
Entrez	1280

Protein

Protein Name	Collagen Type II Alpha 1 Chain
Classification	Collagen
Mol. Weight (kD)	142
UniProtKB	P02458
Protein Domains	IPR000885, IPR001007 May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (0)

Link to hereOther Information

Proteomics

Proteomics

BM Substrates (0)

This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.

BM Ligands (40)

Gene
ADAMTS2
ADAMTS3
ADAMTS5
ADAMTS14
COL4A1
COL4A2
COL4A3
COL4A4
COL4A5
COL4A6
COL5A1
COL6A1
COL6A2
COL6A3
COL7A1
COL8A1
COL8A2
COL9A1
COL9A2
COL9A3
COL15A1
COL17A1
COL18A1
COL28A1
MATN1
P3H1
P3H2
SPARC
TGFB1
TLL1
CD44
COL13A1
ITGA1
ITGA2
ITGA2B
ITGA10
ITGAV
ITGB1
ITGB3
SDC1

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

Interaction Network Images

Associated Diseases (16)

Spondylometaphyseal dysplasia, corner fracture type HPO

Achondrogenesis, Type Ii OMIM

Spondyloperipheral Dysplasia OMIM

Spondyloepimetaphyseal Dysplasia, Strudwick Type OMIM

Stickler Syndrome, Type I, Nonsyndromic Ocular OMIM

Kniest Dysplasia OMIM

Spondyloepiphyseal Dysplasia Congenita OMIM

Czech Dysplasia, Metatarsal Type OMIM

Platyspondylic Lethal Skeletal Dysplasia, Torrance Type OMIM

Epiphyseal dysplasia, multiple, with myopia and deafness OMIM

Spondyloepiphyseal Dysplasia, Stanescu Type OMIM

Osteoarthritis With Mild Chondrodysplasia; OMIM

Legg-calve-perthes Disease OMIM

Stickler Syndrome, Type I OMIM

Avascular Necrosis Of Femoral Head, Primary, 1 OMIM

Spondylometaphyseal dysplasia, corner fracture type OMIM

This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereOrthology

Orthologs by Species

Zebrafish (Danio rerio) — 1 ortholog(s) of COL2A1

Mouse (Mus musculus) — 1 ortholog(s) of COL2A1

Link to hereSee also

External References

Entrez/1280 UniProtKB/P02458 Publication: A basement membrane discovery pipeline/sciadv.abn2265

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.