SPARC
Ab — Antibody evidence. See Protein Localisation. Tag — Tagged gene or ortholog. See Protein Localisation. Int — Basement membrane interaction. See Interactions.
Entry ID: BMB30964
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Gene & Protein
Protein Localisation
Interactions
Associated Diseases
Multiomics
Orthology
See also
Gene
| Species | Human (Homo sapiens) |
| Gene Symbol | SPARC |
| Gene Size (Bases) | 25880 |
| Entrez | 6678 |
Protein
| Protein Name | Secreted Protein Acidic And Cysteine Rich |
| Classification | ECM glycoprotein |
| Mol. Weight (kD) | 35 |
| UniProtKB | P09486 |
| Protein Domains |
SPARC/Testican, calcium-binding domain , Follistatin/Osteonectin EGF domain , Kazal domain , Follistatin-like, N-terminal , Kazal domain superfamily
+ 4 more…
May not be up to date — see InterPro .
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Link to hereProtein Localisation
Localisation Images (1)
Localisation Evidence (4)
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Patterns of SPARC expression and basement membrane intactness at the tumour-brain border of invasive meningiomas. PubMedFound in: Human (Homo sapiens)Reagents: Anti-SPARC mAb (Harmatological Technologies)Comment: See Fig. 1
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Found in: Human (Homo sapiens)Reagents: Goat anti-SPARC pAb (R&D systems, AF941)Comment: See Fig. 2
Link to hereInteractions
BM Ligands (27)
| Gene |
|---|
| BGN |
| COL2A1 |
| COL4A1 |
| COL4A2 |
| COL5A1 |
| COL6A1 |
| COL18A1 |
| DCN |
| FN1 |
| HSPG2 |
| ISLR |
| LUM |
| MMP2 |
| NID1 |
| PAPLN |
| POSTN |
| PTN |
| RECK |
| SMOC1 |
| SPOCK1 |
| SPOCK3 |
| TGFB2 |
| TGFB1 |
| THBS1 |
| THBS2 |
| TIMP1 |
| VTN |
This list has been manually curated and may not be the most up to date. Further updates may be available on
STRING .
BM Substrates (0)
Interaction Network Images
Link to hereAssociated Diseases
Associated Diseases (1)
Link to hereMultiomics
Link to hereOrthology
Orthologs by Species
Link to hereSee also
External References
If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.