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BGN

Ab — Antibody evidence. See Protein Localisation. Int — Basement membrane interaction. See Interactions.
Entry ID: BMB30513
Gene
Species Human (Homo sapiens)
Gene Symbol BGN
Gene Size (Bases) 14567
Entrez 633
Protein
Protein Name Biglycan
Classification Proteoglycan
Mol. Weight (kD) 42
UniProtKB P21810
Protein Domains Leucine-rich repeat N-terminal domain , Leucine-rich repeat , Leucine-rich repeat, typical subtype , Leucine-rich repeat domain superfamily , Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan + 1 more…
May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (0)
Localisation Evidence (4)

Link to hereInteractions

BM Ligands (41)
Gene
ACAN
ADAMTS4
AGRN
BCAN
COL4A1
COL5A1
COL6A1
COL6A2
COL6A3
COL12A1
COL18A1
DCN
EFEMP2
FBLN2
FBN1
FMOD
FN1
HSPG2
LOXL1
LUM
MMP2
NID1
POSTN
SPARC
TGFB2
TGFB1
TGFBI
THBS1
VCAN
VTN
CD44
DAG1
GPC1
GPC2
GPC3
GPC4
GPC5
GPC6
SDC4
SDC1
COL5A2
This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .
BM Substrates (0)
Interaction Network Images

Link to hereAssociated Diseases

Associated Diseases (2)
Meester-Loeys syndrome OMIM
Spondyloepimetaphyseal dysplasia, X-linked OMIM
This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereMultiomics

Proteomics
Proteomics evidence available

Link to hereOrthology

Orthologs by Species
Zebrafish (Danio rerio) — 2 ortholog(s) of BGN
Mouse (Mus musculus) — 1 ortholog(s) of BGN

Link to hereSee also

External References
If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.