COL18A1 (Collagen Type XVIII Alpha 1 Chain) in Human (Homo sapiens) - bmBASE - A resource for basement membrane research

IPR001791:Laminin G domain, IPR010515:Collagenase NC10/endostatin domain, IPR010363:Domain of unknown function DUF959, collagen XVIII, N-terminal domain, IPR020067:Frizzled domain, IPR035523:Collagen alpha-1(XVIII) chain, frizzled domain

This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species

Caenorhabditis elegans — 1 ortholog(s) of COL18A1 Tag

Zebrafish (Danio rerio) — 2 ortholog(s) of COL18A1

Drosophila — 1 ortholog(s) of COL18A1

Mouse (Mus musculus) — 1 ortholog(s) of COL18A1

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (2)

Mapping the differential distribution of proteoglycan core proteins in the adult human retina, choroid, and sclera PubMed

Found in: Human (Homo sapiens)

Reagents: collagen XVIII 6C4 mAb (Developmental Studies Hybridoma Bank)
Characterization of extracellular matrix components in the limbal epithelial stem cell compartment. PubMed

Found in: Human (Homo sapiens)

Reagents: mouse col XVIII NC11 domain

Link to hereOther Information

Proteomics

BM Substrates (0)

This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.

BM Ligands (42)

Gene
ADAMTS8
ADAMTS18
COL2A1
COL4A1
COL4A2
COL4A3
COL4A4
COL4A5
COL4A6
COL5A1
COL6A1
COL6A2
COL6A3
COL7A1
COL8A1
COL8A2
COL9A1
COL9A2
COL9A3
COL15A1
COL17A1
COL28A1
CTSB
CTSD
HSPG2
LAMA1
LAMB1
LAMC1
MMP2
MMP7
P3H1
P3H2
THBS1
COL13A1
GPC1
GPC4
ITGA3
ITGA5
ITGAV
ITGB1
ITGB3
ITGB5

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

Associated Diseases (1)

Knobloch syndrome 1 OMIM

This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References

Entrez/80781 UniProtKB/P39060

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.