CSPG4

Int — Basement membrane interaction. See Interactions.

Entry ID: BMB31093

Protein Localisation

Associated Diseases

Gene

Species	Human (Homo sapiens)
Gene Symbol	CSPG4
Gene Size (Bases)	38527
Entrez	1464

Protein

Protein Name	Chondroitin Sulfate Proteoglycan 4
Classification	ECM-affiliated protein
Mol. Weight (kD)	251
UniProtKB	Q6UVK1
Protein Domains	Laminin G domain , Laminin G domain , Concanavalin A-like lectin/glucanase domain superfamily , CSPG repeat , FRAS1-related extracellular matrix May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (1)

Diversified expression of NG2/CSPG4 isoforms in glioblastoma and human foetal brain identifies pericyte subsets PubMed

Found in: Human (Homo sapiens)

Reagents: α-CSPG4 mAb - clone 2164H5, in-house

Comment: See Fig. 2

Link to hereInteractions

BM Ligands (5)

Gene
AGRN
BCAN
DCN
HSPG2
GPC1

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

BM Substrates (0)

Interaction Network Images

Link to hereAssociated Diseases

Associated Diseases (0)

Link to hereMultiomics

Proteomics

Proteomics evidence available

Matrisome Project/ECM-affiliated Proteins

proteinBASE/Human podocyte proteomics

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices. PubMed

Link to hereOrthology

Orthologs by Species

Caenorhabditis elegans — 1 ortholog(s) of CSPG4

Zebrafish (Danio rerio) — 1 ortholog(s) of CSPG4

Drosophila — 1 ortholog(s) of CSPG4

Mouse (Mus musculus) — 1 ortholog(s) of CSPG4

Link to hereSee also

External References

Publication: A basement membrane discovery pipeline/sciadv.abn2265

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.