BCAN (Brevican) in Human (Homo sapiens) - bmBASE - A resource for basement membrane research

IPR000436:Sushi/SCR/CCP domain, IPR000538:Link domain, IPR000742:EGF-like domain, IPR001304:C-type lectin-like domain, IPR003599:Immunoglobulin subtype domain, IPR007110:Immunoglobulin-like domain, IPR013106:Immunoglobulin V-set domain

This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species

Zebrafish (Danio rerio) — 1 ortholog(s) of BCAN

Mouse (Mus musculus) — 1 ortholog(s) of BCAN

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (2)

Mapping the differential distribution of proteoglycan core proteins in the adult human retina, choroid, and sclera PubMed

Found in: Human (Homo sapiens)

Reagents: mAb brevican clone 450616 (R&D systems)
Extracellular matrix component expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix PubMed

Found in: Human (Homo sapiens)

Reagents: rabbit pAb BCAN (Abcam ab111719)

Link to hereOther Information

Proteomics

BM Substrates (0)

This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.

BM Ligands (10)

Gene
TNC
VCAN
GPC1
GPC2
GPC3
GPC4
GPC5
GPC6
SDC4
SDC1

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

Associated Diseases (0)

This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References

Entrez/63827 UniProtKB/Q96GW7

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.