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GPC3

Tag — Tagged gene or ortholog. See Protein Localisation. Int — Basement membrane interaction. See Interactions.
Entry ID: BMB31148
Gene
Species Human (Homo sapiens)
Gene Symbol GPC3
Gene Size (Bases) 449872
Entrez 2719
Protein
Protein Name Glypican 3
Classification ECM-affiliated protein
Mol. Weight (kD) 66
UniProtKB P51654
Protein Domains Glypican , Glypican, conserved site
May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (0)
Localisation Evidence (0)

Link to hereInteractions

BM Ligands (18)
Gene
AGRN
AMELX
AMTN
BCAN
BGN
CST3
DCN
FBN1
FN1
HSPG2
LAMB1
LAMB2
LAMC1
GPC1
GPC2
GPC4
UNC5D
SDC1
This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .
BM Substrates (0)
Interaction Network Images

Link to hereAssociated Diseases

Associated Diseases (2)
Simpson-Golabi-Behmel syndrome, type 1 OMIM
Wilms tumor 1 OMIM
This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereMultiomics

Proteomics
Proteomics evidence available

Link to hereOrthology

Orthologs by Species
Caenorhabditis elegans — 1 ortholog(s) of GPC3 Tag
Zebrafish (Danio rerio) — 1 ortholog(s) of GPC3
Drosophila — 1 ortholog(s) of GPC3
Mouse (Mus musculus) — 1 ortholog(s) of GPC3

Link to hereSee also

External References
Publication: A basement membrane discovery pipeline/sciadv.abn2265
If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.