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CST3

Int — Basement membrane interaction. See Interactions.
Entry ID: BMB30612
Gene
Species Human (Homo sapiens)
Gene Symbol CST3
Gene Size (Bases) 11768
Entrez 1471
Protein
Protein Name Cystatin C
Classification ECM regulator
Mol. Weight (kD) 16
UniProtKB P01034
Protein Domains Cystatin domain , Proteinase inhibitor I25, cystatin, conserved site , Cystatin superfamily
May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (0)
Localisation Evidence (1)

Link to hereInteractions

BM Ligands (19)
Gene
AMELX
AMTN
CTSB
CTSD
FBN1
FN1
HSPG2
LAMB1
LAMB2
LAMC1
SPARCL1
TIMP1
TIMP2
TNC
VCAN
VWA1
ADAM10
EVA1A
GPC3
This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .
BM Substrates (0)
Interaction Network Images

Link to hereAssociated Diseases

Associated Diseases (2)
Macular degeneration, age-related, 11 HPO
Amyloidosis Vi HPO
This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereMultiomics

Proteomics

Link to hereOrthology

Orthologs by Species
Caenorhabditis elegans — 3 ortholog(s) of CST3
Zebrafish (Danio rerio) — 1 ortholog(s) of CST3
Drosophila — 2 ortholog(s) of CST3
Mouse (Mus musculus) — 1 ortholog(s) of CST3

Link to hereSee also

External References
Publication: A basement membrane discovery pipeline/sciadv.abn2265
If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.