RECK

Int — Basement membrane interaction. See Interactions. Pred — Predicted BM component. Included based on predicted interaction, domain analysis, or secretion signal.

Entry ID: BMB30920

Protein Localisation

Associated Diseases

Gene

Species	Human (Homo sapiens)
Gene Symbol	RECK
Gene Size (Bases)	87551
Entrez	8434

Protein

Protein Name	Reversion Inducing Cysteine Rich Protein With Kazal Motifs
Classification	ECM regulator
Mol. Weight (kD)	106
UniProtKB	O95980
Protein Domains	Kazal domain , Kazal domain superfamily , Reversion-inducing cysteine-rich protein with Kazal motifs , Reversion-inducing cysteine-rich protein with Kazal, CC4 domain , Reversion-inducing cysteine-rich protein with Kazal, EGF-like 1 domain , RECK, EGF-like 2 domain + 4 more… May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (0)

Link to hereInteractions

BM Ligands (6)

Gene
MMP2
SPARC
TIMP2
TIMP3
MMP14
MMP9

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

BM Substrates (0)

Interaction Network Images

Link to hereAssociated Diseases

Associated Diseases (0)

Link to hereMultiomics

Proteomics

proteinBASE/Human podocyte proteomics

Link to hereOrthology

Orthologs by Species

Zebrafish (Danio rerio) — 1 ortholog(s) of RECK

Drosophila — 1 ortholog(s) of RECK

Mouse (Mus musculus) — 1 ortholog(s) of RECK

Link to hereSee also

External References

Publication: A basement membrane discovery pipeline/sciadv.abn2265

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.