Cst3

Ab — Antibody evidence. See Protein Localisation.

Entry ID: BMB30613

Protein Localisation

Associated Diseases

Gene

Species	Mouse (Mus musculus)
Gene Symbol	Cst3
Gene Size (Bases)	3791
Entrez	13010

Protein

Protein Name	Cystatin C
Classification	ECM regulator (Matrisome Project list )
Mol. Weight (kD)	15
UniProtKB	P21460
Protein Domains	Cystatin domain , Proteinase inhibitor I25, cystatin, conserved site , Cystatin superfamily May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (1)

VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation. PubMed

Found in: Mouse (Mus musculus)

Reagents: Cystatin C antibody (R&D Systems)

Link to hereInteractions

BM Ligands (0)

Link to hereAssociated Diseases

Associated Diseases (2)

Diseases listed for this gene are inferred from its human ortholog(s) in OMIM.

Cerebral amyloid angiopathy OMIM

Leukodystrophy, adult-onset, autosomal dominant, without amyloid angiopathy OMIM

This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM .

Link to hereMultiomics

Proteomics

proteinBASE/Mouse kidney proteomics

Link to hereOrthology

Orthologs by Species

Caenorhabditis elegans — 3 ortholog(s) of Cst3

Human (Homo sapiens) — 1 ortholog(s) of Cst3

Link to hereSee also

External References

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.