CTSB (Cathepsin B) in Human (Homo sapiens) - bmBASE - A resource for basement membrane research

CTSB EnzInt

Entry ID: BMB30629

Enz — Basement membrane protease. See the BM Substrates tab.

Int — Basement membrane interaction. See the BM Ligands tab.

Link to hereGene

Species

Human (Homo sapiens)

Gene Symbol

CTSB

Gene Size (Bases)

26925

Link to hereProtein

Protein Name

Cathepsin B

Protein Classification

ECM regulator

Protein Molecular Weight (kD)

Protein Domains

IPR012599:Peptidase C1A, propeptide domain, IPR000668:Peptidase C1A, papain C-terminal domain

This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species

Caenorhabditis elegans — 9 ortholog(s) of CTSB

Zebrafish (Danio rerio) — 2 ortholog(s) of CTSB

Drosophila — 1 ortholog(s) of CTSB

Mouse (Mus musculus) — 1 ortholog(s) of CTSB

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (0)

Link to hereOther Information

Proteomics

BM Substrates (1)

FN1

This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.

BM Ligands (4)

Gene
COL15A1
COL18A1
CST3
CTSD

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

Associated Diseases (1)

Keratolytic winter erythema HPO

This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References

Entrez/1508 UniProtKB/P07858

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.