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CTSD EnzInt
Entry ID: BMB30643
Enz — Basement membrane protease. See the BM Substrates tab.
Int — Basement membrane interaction. See the BM Ligands tab.

Link to hereGene

Species
Human (Homo sapiens)
Gene Symbol
CTSD
Gene Size (Bases)
11819

Link to hereProtein

Protein Name
Cathepsin D
Protein Classification
ECM regulator
Protein Molecular Weight (kD)
45
Protein Domains
IPR012848:Aspartic peptidase, N-terminal domain, IPR033121:Peptidase family A1 domain
This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species
Caenorhabditis elegans — 3 ortholog(s) of CTSD
Zebrafish (Danio rerio) — 1 ortholog(s) of CTSD
Drosophila — 1 ortholog(s) of CTSD
Mouse (Mus musculus) — 1 ortholog(s) of CTSD

Link to hereProtein Localisation

Localisation Images (0)
Localisation Evidence (1)

Link to hereOther Information

Proteomics
BM Substrates (2)
CTSB, FN1
This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.
BM Ligands (5)
Gene
COL18A1
CST3
CTSA
CTSB
TIMP2
This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .
Associated Diseases (1)
Ceroid lipofuscinosis, neuronal, 10 HPO
This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References
Entrez/1509 UniProtKB/P07339
If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.