Hmcn1

Ab — Antibody evidence. See Protein Localisation. Tag — Tagged gene or ortholog. See Protein Localisation.

Entry ID: BMB30731

Protein Localisation

Associated Diseases

Gene

Species	Mouse (Mus musculus)
Gene Symbol	Hmcn1
Gene Size (Bases)	430912
Entrez	545370

Protein

Protein Name	Hemicentin 1
Classification	ECM glycoprotein
Mol. Weight (kD)	612
UniProtKB	D3YXG0
Protein Domains	EGF-like domain , Immunoglobulin domain subtype , Immunoglobulin-like domain , Immunoglobulin V-set domain , Immunoglobulin subtype 2 , Immunoglobulin I-set , EGF-like calcium-binding domain , Complement Clr-like EGF domain , G2 nidogen/fibulin G2F , Thrombospondin type-1 (TSP1) repeat , Immunoglobulin-like fold , Green fluorescent protein + 17 more… May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (2)

Mammalian hemicentin 1 is assembled into tracks in the extracellular matrix of multiple tissues. PubMed

Found in: Mouse (Mus musculus)

Reagents: anti-fibulin domains of HMCN1, in-house

Comment: See Figure 3
Hemicentin 1 influences podocyte dynamic changes in glomerular diseases. PubMed

Found in: Mouse (Mus musculus)

Reagents: anti-Fibulin6 (Merch Millipore, AB6066)

Comment: See Figure 3

Link to hereInteractions

BM Substrates (0)

BM Ligands (0)

Interaction Network Images

Link to hereAssociated Diseases

Associated Diseases (0)

Link to hereMultiomics

Proteomics

proteinBASE/Mouse kidney proteomics

Link to hereOrthology

Orthologs by Species

Caenorhabditis elegans — 1 ortholog(s) of Hmcn1 Tag

Zebrafish (Danio rerio) — 1 ortholog(s) of Hmcn1

Drosophila — 1 ortholog(s) of Hmcn1

Human (Homo sapiens) — 1 ortholog(s) of Hmcn1

Link to hereSee also

External References

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