SMC3

Ab — Antibody evidence. See Protein Localisation.

Entry ID: BMB30949

Protein Localisation

Associated Diseases

Gene

Species	Human (Homo sapiens)
Gene Symbol	SMC3
Gene Size (Bases)	38354
Entrez	9126

Protein

Protein Name	Structural Maintenance Of Chromosomes 3
Classification
Mol. Weight (kD)	142
UniProtKB	Q9UQE7
Protein Domains	SMCs flexible hinge , Structural maintenance of chromosomes 3, ABC domain, eukaryotic , RecF/RecN/SMC, N-terminal , P-loop containing nucleoside triphosphate hydrolase , Structural maintenance of chromosomes protein , SMCs flexible hinge superfamily + 1 more… May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (2)

cDNA cloning of the basement membrane chondroitin sulfate proteoglycan core protein, bamacan: a five domain structure including coiled-coil motifs PubMed

Found in: Human (Homo sapiens)

Reagents: Anti-bamacan pAb R664, in house

Comment: See Fig. 9
Extracellular matrix alterations in human corneas with bullous keratopathy PubMed

Found in: Human (Homo sapiens)

Reagents: Rb anti-rat bamacan pAb, in house

Comment: See Fig. 3

Link to hereInteractions

BM Substrates (0)

BM Ligands (0)

Interaction Network Images

Link to hereAssociated Diseases

Associated Diseases (1)

Cornelia de Lange syndrome 3 OMIM

This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereMultiomics

Proteomics

proteinBASE/Human podocyte proteomics

Link to hereOrthology

Orthologs by Species

Caenorhabditis elegans — 1 ortholog(s) of SMC3

Zebrafish (Danio rerio) — 1 ortholog(s) of SMC3

Drosophila — 1 ortholog(s) of SMC3

Mouse (Mus musculus) — 1 ortholog(s) of SMC3

Link to hereSee also

External References

Publication: A basement membrane discovery pipeline/sciadv.abn2265

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.