daf-7

Int — Basement membrane interaction. See BM Ligands. Pred — Predicted BM component. Included based on predicted interaction, domain analysis, or secretion signal.

Entry ID: BMB30998

Gene & Protein

Protein Localisation

Other Information

Orthology

Gene

Species	Caenorhabditis elegans
Gene Symbol	daf-7
Gene Size (Bases)	1930
Entrez	175237

Protein

Protein Name	DAF-7
Classification	Secreted factor
Mol. Weight (kD)	40
UniProtKB	P92172
Protein Domains	Transforming growth factor-beta, C-terminal May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (0)

Link to hereOther Information

Proteomics

proteinBASE/C. elegans proteomics

BM Substrates (0)

This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.

BM Ligands (3)

Gene
daf-1
daf-4
sma-6

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

Interaction Network Images

Associated Diseases (4)

Loeys-dietz Syndrome, Type 4 OMIM

Cystic Fibrosis OMIM

Inflammatory Bowel Disease, Immunodeficiency, And Encephalopathy OMIM

Camurati-engelmann Disease OMIM

This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereOrthology

Orthologs by Species

Zebrafish (Danio rerio) — 2 ortholog(s) of daf-7

Drosophila — 1 ortholog(s) of daf-7

Human (Homo sapiens) — 2 ortholog(s) of daf-7

Mouse (Mus musculus) — 2 ortholog(s) of daf-7

Link to hereSee also

External References

Publication: A basement membrane discovery pipeline/sciadv.abn2265

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.