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TIMP3 Int
Entry ID: BMB31032
Int — Basement membrane interaction. See the BM Ligands tab.

Link to hereGene

Species
Human (Homo sapiens)
Gene Symbol
TIMP3
Gene Size (Bases)
61343

Link to hereProtein

Protein Name
TIMP Metallopeptidase Inhibitor 3
Protein Classification
ECM regulator
Protein Molecular Weight (kD)
24
Protein Domains
IPR001134:Netrin domain
This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species
Caenorhabditis elegans — 2 ortholog(s) of TIMP3
Zebrafish (Danio rerio) — 1 ortholog(s) of TIMP3
Drosophila — 1 ortholog(s) of TIMP3
Mouse (Mus musculus) — 1 ortholog(s) of TIMP3

Link to hereProtein Localisation

Localisation Images (0)
Localisation Evidence (1)

Link to hereOther Information

Proteomics
BM Substrates (0)
This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.
BM Ligands (11)
Gene
ADAMTS3
ADAMTS4
ADAMTS5
ECM1
EFEMP1
MMP1
MMP2
MMP7
RECK
TIMP2
MMP14
This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .
Associated Diseases (1)
Sorsby fundus dystrophy OMIM
This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References
Entrez/7078 UniProtKB/P35625
If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.