Vwa2

Ab — Antibody evidence. See Protein Localisation.

Entry ID: BMB31066

Protein Localisation

Associated Diseases

Gene

Species	Mouse (Mus musculus)
Gene Symbol	Vwa2
Gene Size (Bases)	37663
Entrez	240675

Protein

Protein Name	Von Willebrand Factor A Domain Containing 2
Classification	ECM glycoprotein (Matrisome Project list )
Mol. Weight (kD)	86
UniProtKB	Q70UZ7
Protein Domains	EGF-like domain , EGF-like calcium-binding domain , von Willebrand factor, type A , EGF-like, conserved site , von Willebrand factor A-like domain superfamily + 1 more… May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (5)

Mouse AMACO, a kidney and skin basement membrane associated molecule that mediates RGD-dependent cell attachment. PubMed

Found in: Mouse (Mus musculus)

Reagents: Rb anti-AMACO-P3, in house

Comment: See Fig. 1
A homozygous missense variant in VWA2, encoding an interactor of the Fraser-complex, in a patient with vesicoureteral reflux. PubMed

Found in: Mouse (Mus musculus)

Reagents: Guinea pig anti-human/mouse P3 fragments (VWA2), in house

Comment: See Fig. 3
Identification and characterization of AMACO, a new member of the von Willebrand factor A-like domain protein superfamily with a regulated expression in the kidney. PubMed

Found in: Mouse (Mus musculus)

Reagents: Rb anti-AMACO, in house

Comment: See Fig. 6
AMACO is a component of the basement membrane-associated Fraser complex. PubMed

Found in: Mouse (Mus musculus)

Reagents: Rb anti-AMACO-P3, in house

Comment: See Fig. 2
Anchoring Cords: A Distinct Suprastructure in the Developing Skin. PubMed

Found in: Mouse (Mus musculus)

Reagents: a-AMACO (VWA2) pAb (guinea pig; Gebauer et al., 2009)

Link to hereInteractions

BM Ligands (0)

Link to hereAssociated Diseases

Associated Diseases (0)

Link to hereMultiomics

Proteomics

proteinBASE/Mouse kidney proteomics

Link to hereOrthology

Orthologs by Species

Zebrafish (Danio rerio) — 1 ortholog(s) of Vwa2

Human (Homo sapiens) — 1 ortholog(s) of Vwa2

Link to hereSee also

External References

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