Dcc

Ab — Antibody evidence. See Protein Localisation. Int — Basement membrane interaction. See Interactions.

Entry ID: BMB31108

Protein Localisation

Associated Diseases

Gene

Species	Mouse (Mus musculus)
Gene Symbol	Dcc
Gene Size (Bases)	1097436
Entrez	13176

Protein

Protein Name	DCC Netrin 1 Receptor
Classification	Receptor
Mol. Weight (kD)	158
UniProtKB	P70211
Protein Domains	Immunoglobulin domain subtype , Immunoglobulin-like domain , Immunoglobulin subtype 2 , Fibronectin type III , Neogenin, C-terminal , Immunoglobulin I-set , Fibronectin type III superfamily , Immunoglobulin-like fold + 4 more… May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (2)

Lack of netrin-4 modulates pathologic neovascularization in the eye. PubMed

Found in: Mouse (Mus musculus)

Reagents: Rabbit anti-DCC antibody, in house

Comment: See Fig. 5
Revisiting the role of Dcc in visual system development with a novel eye clearing method. PubMed

Found in: Mouse (Mus musculus)

Reagents: anti-DCC pAb (Santa Cruz, sc-6535)

Comment: See Fig. 1 and 7

Link to hereInteractions

BM Ligands (6)

Gene
Ntn1
Ntn4
Unc5a
Unc5b
Unc5c
Unc5d

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

BM Substrates (0)

Interaction Network Images

Link to hereAssociated Diseases

Associated Diseases (0)

Link to hereMultiomics

Proteomics

proteinBASE/Mouse kidney proteomics

Link to hereOrthology

Orthologs by Species

Caenorhabditis elegans — 1 ortholog(s) of Dcc

Zebrafish (Danio rerio) — 1 ortholog(s) of Dcc

Drosophila — 1 ortholog(s) of Dcc

Human (Homo sapiens) — 1 ortholog(s) of Dcc

Link to hereSee also

External References

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.