MEP1B (Meprin A Subunit Beta) in Human (Homo sapiens) - bmBASE - A resource for basement membrane research

IPR000742:EGF-like domain, IPR000998:MAM domain, IPR006026:Peptidase, metallopeptidase domain, IPR001506:Peptidase M12A domain, IPR002083:MATH/TRA domain, IPR034038:Meprin peptidase domain

This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species

Zebrafish (Danio rerio) — 1 ortholog(s) of MEP1B

Drosophila — 1 ortholog(s) of MEP1B

Mouse (Mus musculus) — 1 ortholog(s) of MEP1B

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (1)

The alpha and beta subunits of the metalloprotease meprin are expressed in separate layers of human epidermis, revealing different functions in keratinocyte proliferation and differentiation. PubMed

Found in: Human (Homo sapiens)

Reagents: HPA029119

Comment: See Figure 2

Link to hereOther Information

Proteomics

BM Substrates (7)

ADAM10, ADAM17, ADAM9, FN1, MMP1, NID1, TNC

This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.

BM Ligands (1)

Gene
MEP1A

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

Associated Diseases (0)

This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References

Entrez/4225 UniProtKB/Q16820

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.