Agrn

Ab — Antibody evidence. See Protein Localisation. Tag — Tagged gene or ortholog. See Protein Localisation. Int — Basement membrane interaction. See Interactions.

Entry ID: BMB30501

Gene & Protein

Protein Localisation

Gene

Species	Mouse (Mus musculus)
Gene Symbol	Agrn
Gene Size (Bases)	32199
Entrez	11603

Protein

Protein Name	Agrin
Classification	ECM glycoprotein
Mol. Weight (kD)	207
UniProtKB	A2ASQ1
Protein Domains	EGF-like domain , SEA domain , Laminin G domain , EGF-like calcium-binding domain , Laminin-type EGF domain , Kazal domain , Follistatin-like, N-terminal , Factor I / membrane attack complex , Kazal domain superfamily , SEA domain superfamily + 7 more… May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (2)

Glial dystrophin-associated proteins, laminin and agrin, are downregulated in the brain of mdx mouse. PubMed

Found in: Mouse (Mus musculus)

Reagents: anti-agrin 131 mouse mAb (Stressgen Bioreagents, Victoria, BC, Canada)
Agrin immunohistochemistry Matrixome project

Found in: Mouse (Mus musculus)

Reagents: Rabbit pAb ag1 (MATRIXOME PJ)

Comment: The Matrixome Project, agrin E16.5 Whole body

Link to hereInteractions

BM Ligands (5)

Gene
Fn1
Hspg2
Nid1
Dag1
Musk

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

Interaction Network Images

Link to hereAssociated Diseases

Associated Diseases (0)

Link to hereMultiomics

Proteomics

proteinBASE/Mouse kidney proteomics

Link to hereOrthology

Orthologs by Species

Caenorhabditis elegans — 1 ortholog(s) of Agrn Tag

Zebrafish (Danio rerio) — 1 ortholog(s) of Agrn

Human (Homo sapiens) — 1 ortholog(s) of Agrn

Link to hereSee also

External References

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.