Frem2

Ab — Antibody evidence. See Protein Localisation.

Entry ID: BMB30717

Protein Localisation

Other Information

Gene

Species	Mouse (Mus musculus)
Gene Symbol	Frem2
Gene Size (Bases)	143418
Entrez

Protein

Protein Name	FRAS1 Related Extracellular Matrix 2
Classification	ECM-affiliated protein
Mol. Weight (kD)	351
UniProtKB
Protein Domains

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (4)

Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa. PubMed

Found in: Mouse (Mus musculus)

Reagents: anti-FREM2 rb pAb

Comment: See Figure 1
Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development. PubMed

Found in: Mouse (Mus musculus)

Reagents: anti-FREM2 rb pAb

Comment: See Figures 1-5
Frem3, a member of the 12 CSPG repeats-containing extracellular matrix protein family, is a basement membrane protein with tissue distribution patterns distinct from those of Fras1, Frem2, and QBRICK/Frem1 PubMed

Found in: Mouse (Mus musculus)

Reagents: anti-FREM2 rb pAb (2)

Comment: See Figure 3
Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects PubMed

Found in: Mouse (Mus musculus)

Reagents: anti-FREM2 rb pAb (2)

Comment: See Figure 3

Link to hereOther Information

Proteomics

BM Substrates (0)

This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.

BM Ligands (0)

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

Interaction Network Images

Associated Diseases (0)

This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereOrthology

Orthologs by Species

Caenorhabditis elegans — 1 ortholog(s) of Frem2

Zebrafish (Danio rerio) — 2 ortholog(s) of Frem2

Human (Homo sapiens) — 1 ortholog(s) of Frem2

Link to hereSee also

External References

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