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lam-3

Tag — Tagged gene or ortholog. See Protein Localisation. Int — Basement membrane interaction. See BM Ligands.
Entry ID: BMB30754
Gene
Species Caenorhabditis elegans
Gene Symbol lam-3
Gene Size (Bases) 12970
Entrez
Protein
Protein Name LAM-3
Classification ECM glycoprotein
Mol. Weight (kD) 344
UniProtKB G5ECE3
Protein Domains IPR000742, IPR001791, IPR000034, IPR002049, IPR008211
May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (2)

lam-3 CRISPR knock-in information

LAM-3::mNG in embryo
Localisation Evidence (1)

Link to hereOther Information

Proteomics
BM Substrates (0)
This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.
BM Ligands (7)
Gene
lam-1
lam-2
nid-1
dgn-1
pat-2
ina-1
pat-3
This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .
Interaction Network Images
Associated Diseases (7)
Poretti-boltshauser Syndrome HPO
Muscular dystrophy, limb-girdle, autosomal recessive 23 HPO
Muscular Dystrophy, Congenital Merosin-deficient, 1a HPO
Epidermolysis bullosa, junctional, non-Herlitz type HPO
Epidermolysis bullosa, junctional, Herlitz type HPO
Laryngoonychocutaneous syndrome HPO
Cardiomyopathy, dilated, 1jj HPO
This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereOrthology

Orthologs by Species
Zebrafish (Danio rerio) — 5 ortholog(s) of lam-3
Drosophila — 2 ortholog(s) of lam-3
Human (Homo sapiens) — 5 ortholog(s) of lam-3
Mouse (Mus musculus) — 5 ortholog(s) of lam-3

Link to hereSee also

External References
UniProtKB/G5ECE3 CGC Strains/NK2425 Publication: A basement membrane discovery pipeline/sciadv.abn2265
If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.