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lam-2

Tag — Tagged gene or ortholog. See Protein Localisation. Int — Basement membrane interaction. See Interactions.
Entry ID: BMB30785
Gene
Species Caenorhabditis elegans
Gene Symbol lam-2
Gene Size (Bases) 7394
Entrez 180980
Protein
Protein Name LAM-2
Classification ECM glycoprotein
Mol. Weight (kD) 181
UniProtKB Q18823
Protein Domains EGF-like domain , Laminin-type EGF domain , Laminin IV , Laminin-type EGF domain , Laminin, N-terminal + 2 more…
May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (3)

lam-2 CRISPR knock-in information

LAM-2::mNG in embryo

LAM-2::mNG in L1 pharynx
Localisation Evidence (2)

Link to hereInteractions

BM Ligands (7)
Gene
epi-1
lam-3
lam-1
nid-1
dgn-1
ina-1
pat-3
This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .
BM Substrates (0)
Interaction Network Images

Link to hereAssociated Diseases

Associated Diseases (3)
Epidermolysis bullosa, junctional, non-Herlitz type HPO
Epidermolysis bullosa, junctional, Herlitz type HPO
Cortical malformations, occipital HPO
This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereMultiomics

Proteomics

Link to hereOrthology

Orthologs by Species
Zebrafish (Danio rerio) — 3 ortholog(s) of lam-2
Drosophila — 1 ortholog(s) of lam-2
Human (Homo sapiens) — 3 ortholog(s) of lam-2
Mouse (Mus musculus) — 3 ortholog(s) of lam-2

Link to hereSee also

External References
CGC Strains/NK2335 CGC Strains/NK2446 Publication: A basement membrane discovery pipeline/sciadv.abn2265
If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.