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lam-1

Tag — Tagged gene or ortholog. See Protein Localisation. Int — Basement membrane interaction. See Interactions.
Entry ID: BMB30773
Gene
Species Caenorhabditis elegans
Gene Symbol lam-1
Gene Size (Bases) 10415
Entrez 172687
Protein
Protein Name LAM-1
Classification ECM glycoprotein
Mol. Weight (kD) 198
UniProtKB O44565 Q21443
Protein Domains EGF-like domain , Laminin-type EGF domain , Laminin, N-terminal , Laminin IV type B , Intermediate filament, rod domain + 2 more…
May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (3)

lam-1 CRISPR knock-in information

LAM-1::mNG in embryo

LAM-1::mNG in L1 pharynx
Localisation Evidence (1)

Link to hereInteractions

BM Ligands (12)
Gene
epi-1
lam-3
lam-2
nid-1
ost-1
sup-17
dgn-1
unc-40
ina-1
pat-3
unc-5
sdn-1
This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .
BM Substrates (0)
Interaction Network Images

Link to hereAssociated Diseases

Associated Diseases (6)
Epidermolysis bullosa, junctional, non-Herlitz type HPO
Epidermolysis bullosa, junctional, Herlitz type HPO
Lissencephaly 5 HPO
Nephrotic syndrome, type 5, with or without ocular abnormalitie HPO
Pierson syndrome HPO
Amelogenesis imperfecta, type Ia HPO
This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereMultiomics

Proteomics

Link to hereOrthology

Orthologs by Species
Zebrafish (Danio rerio) — 4 ortholog(s) of lam-1
Drosophila — 1 ortholog(s) of lam-1
Human (Homo sapiens) — 4 ortholog(s) of lam-1
Mouse (Mus musculus) — 3 ortholog(s) of lam-1

Link to hereSee also

External References
Publication: A basement membrane discovery pipeline/sciadv.abn2265
If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.