epi-1 (EPI-1) in Caenorhabditis elegans - bmBASE - A resource for basement membrane research

:IPR010307:Laminin domain II domain, IPR000742:EGF-like domain, IPR001791:Laminin G domain, IPR000034:Laminin IV domain, IPR002049:Laminin EGF domain, IPR008211:Laminin, N-terminal domain

This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species

Zebrafish (Danio rerio) — 5 ortholog(s) of epi-1

Drosophila — 2 ortholog(s) of epi-1

Human (Homo sapiens) — 5 ortholog(s) of epi-1

Mouse (Mus musculus) — 5 ortholog(s) of epi-1

Link to hereProtein Localisation

Localisation Images (3)

epi-1 CRISPR knock-in information

EPI-1::mNG in embryo

EPI-1::mNG in L1 pharynx

Localisation Evidence (1)

Comprehensive Endogenous Tagging of Basement Membrane Components Reveals Dynamic Movement within the Matrix Scaffolding PubMed

Found in: Caenorhabditis elegans

Reagents:

Comment: Tagged strain available at the CGC - link in external resources.

Link to hereOther Information

Proteomics

BM Substrates (0)

This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.

BM Ligands (9)

Gene
let-2
emb-9
lam-1
lam-2
nid-1
dgn-1
pat-2
ina-1
pat-3

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

Associated Diseases (7)

Poretti-boltshauser Syndrome HPO

Muscular dystrophy, limb-girdle, autosomal recessive 23 HPO

Muscular Dystrophy, Congenital Merosin-deficient, 1a HPO

Epidermolysis bullosa, junctional, non-Herlitz type HPO

Epidermolysis bullosa, junctional, Herlitz type HPO

Laryngoonychocutaneous syndrome HPO

Cardiomyopathy, dilated, 1jj HPO

This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References

UniProtKB/Q21313 CGC Strains/NK2404

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.