emb-9

Tag — Tagged gene or ortholog. See Protein Localisation. Int — Basement membrane interaction. See BM Ligands.

Entry ID: BMB30539

Protein Localisation

Other Information

Gene

Species	Caenorhabditis elegans
Gene Symbol	emb-9
Gene Size (Bases)	7567
Entrez

Protein

Protein Name	EMB-9
Classification	Collagen
Mol. Weight (kD)	171
UniProtKB	P17139
Protein Domains	IPR001442 May not be up to date — see InterPro .

Link to hereProtein Localisation

Localisation Images (3)

emb-9 CRISPR knock-in information

EMB-9::mNG in embryo

EMB-9::mNG in L1 pharynx

Localisation Evidence (3)

Comprehensive Endogenous Tagging of Basement Membrane Components Reveals Dynamic Movement within the Matrix Scaffolding PubMed

Found in: Caenorhabditis elegans

Reagents:

Comment: Tagged strains available at the CGC - link in external resources.
A collagen IV fluorophore knock-in toolkit reveals trimer diversity in C. elegans basement membranes. PubMed

Found in: Caenorhabditis elegans

Reagents:

Comment: NK3057/ NK3072: Tagged strains available at the CGC - link in external resources. NK3057, NK3072 ,NK3073 -Tagged strain available at the CGC - link in external resources.
A basement membrane discovery pipeline uncovers network complexity, regulators, and human disease associations Publication: A basement membrane discovery pipeline

Found in: Caenorhabditis elegans

Reagents:

Comment: NK2651, NK2585 -Tagged strain available at the CGC - link in external resources.

Link to hereOther Information

Proteomics

BM Substrates (0)

This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.

BM Ligands (9)

Gene
let-2
fbl-1
unc-52
epi-1
mig-6
ost-1
pat-2
ina-1
pat-3

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

Interaction Network Images

Associated Diseases (4)

Retinal arteries, tortuosity of OMIM

Angiopathy, hereditary, with nephropathy, aneurysms, and muscle cramps OMIM

Brain small vessel disease 1 with or without ocular anomalies OMIM

Microangiopathy and leukoencephalopathy, pontine OMIM

This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereOrthology

Orthologs by Species

Zebrafish (Danio rerio) — 5 ortholog(s) of emb-9

Drosophila — 2 ortholog(s) of emb-9

Human (Homo sapiens) — 6 ortholog(s) of emb-9

Mouse (Mus musculus) — 1 ortholog(s) of emb-9

Link to hereSee also

External References

UniProtKB/P17139 CGC Strains/NK2326 CGC Strains/NK2604 Publication: A basement membrane discovery pipeline/sciadv.abn2265 CGC Strains/NK3057 CGC Strains/NK3072 CGC Strains/NK3073 CGC Strains/NK2651 CGC Strains/NK2585

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.