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MMP2 EnzInt
Entry ID: BMB30834
Enz — Basement membrane protease. See the BM Substrates tab.
Int — Basement membrane interaction. See the BM Ligands tab.

Link to hereGene

Species
Human (Homo sapiens)
Gene Symbol
MMP2
Gene Size (Bases)
116992

Link to hereProtein

Protein Name
Matrix Metallopeptidase 2
Protein Classification
ECM regulator
Protein Molecular Weight (kD)
74
Protein Domains
IPR000562:Fibronectin type II domain, IPR006026:Peptidase, metallopeptidase domain, IPR000585:Hemopexin-like domain, IPR001818:Peptidase M10, metallopeptidase domain, IPR002477:Peptidoglycan binding-like domain, IPR033739:Peptidase M10A, catalytic domain
This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species
Caenorhabditis elegans — 6 ortholog(s) of MMP2
Zebrafish (Danio rerio) — 1 ortholog(s) of MMP2
Drosophila — 1 ortholog(s) of MMP2
Mouse (Mus musculus) — 1 ortholog(s) of MMP2

Link to hereProtein Localisation

Localisation Images (0)
Localisation Evidence (1)

Link to hereOther Information

Proteomics
BM Substrates (3)
FBLN1, FBLN2, VTN
This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.
BM Ligands (26)
Gene
ACAN
COL5A1
COL6A1
COL6A2
COL18A1
FBN1
LAMA3
LAMB3
LAMC2
MMP1
MMP7
OPTC
POSTN
RECK
SPARC
SPOCK3
TGFB1
THBS1
THBS2
TIMP1
TIMP2
TIMP3
CD44
ITGAM
ITGB2
MMP14
This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .
Associated Diseases (1)
259600 HPO
This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References
Entrez/4313 UniProtKB/P08253
If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.