ADAMTS2 (ADAM Metallopeptidase With Thrombospondin Type 1 Motif 2) in Human (Homo sapiens) - bmBASE - A resource for basement membrane research

IPR001590:Peptidase M12B, ADAM/reprolysin domain, IPR002870:Peptidase M12B, propeptide domain, Peptidase M12B, propeptide:ADAM-TS Spacer 1 domain, IPR010909:PLAC domain, IPR041645:ADAM cysteine-rich domain 2 domain

This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species

Zebrafish (Danio rerio) — 1 ortholog(s) of ADAMTS2

Mouse (Mus musculus) — 1 ortholog(s) of ADAMTS2

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (1)

Human Protein Atlas HPA

Found in: Human (Homo sapiens)

Reagents: ɑ-ADAMTS2 pAb (Atlas Antibodies, HPA028444)

Comment: Human kidney

Link to hereOther Information

Proteomics

BM Substrates (9)

ADAM10, ADAMTS1, DCN, FBLN2, FN1, HSPG2, LOXL1, THBS1, VCAN

This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.

BM Ligands (24)

Gene
ADAMTS1
ADAMTS3
ADAMTS4
ADAMTS5
ADAMTS6
ADAMTS7
ADAMTS8
ADAMTS9
ADAMTS10
ADAMTS13
ADAMTS14
ADAMTS15
ADAMTS16
ADAMTS17
ADAMTS18
ADAMTS19
ADAMTS20
COL2A1
COL5A1
EFEMP2
SPON1
SPON2
THBS1
THBS2

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

Associated Diseases (1)

Ehlers-danlos Syndrome, Type Vii, Autosomal Recessive OMIM

This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References

Entrez/9509 UniProtKB/O95450

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.