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ADAMTS4

EnzInt
Entry ID: BMB30456
Enz — Basement membrane protease. See the BM Substrates tab.
Int — Basement membrane interaction. See the BM Ligands tab.

Link to hereGene

Species
Human (Homo sapiens)
Gene Symbol
ADAMTS4
Gene Size (Bases)
18038

Link to hereProtein

Protein Name
ADAM Metallopeptidase With Thrombospondin Type 1 Motif 4
Protein Classification
ECM regulator
Protein Molecular Weight (kD)
90
Protein Domains
IPR002870:Peptidase M12B, propeptide domain, Peptidase M12B, propeptide:ADAM-TS Spacer 1 domain, IPR041645:ADAM cysteine-rich domain 2 domain, IPR006586:ADAM, cysteine-rich domain
This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species
Zebrafish (Danio rerio) — 1 ortholog(s) of ADAMTS4
Drosophila — 1 ortholog(s) of ADAMTS4
Mouse (Mus musculus) — 1 ortholog(s) of ADAMTS4

Link to hereProtein Localisation

Localisation Images (0)
Localisation Evidence (0)

Link to hereOther Information

Proteomics
BM Substrates (10)
ACAN, BCAN, BGN, DCN, FBLN2, FMOD, FN1, MATN2, SPARCL1, VCAN
This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.
BM Ligands (23)
Gene
ACAN
ADAMTS1
ADAMTS2
ADAMTS3
ADAMTS5
ADAMTS6
ADAMTS7
ADAMTS8
ADAMTS9
ADAMTS10
ADAMTS13
ADAMTS14
ADAMTS15
ADAMTS16
ADAMTS17
ADAMTS18
ADAMTS19
ADAMTS20
SPON1
SPON2
THBS1
THBS2
TIMP3
This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .
Associated Diseases (0)
This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References
Entrez/9507 UniProtKB/O75173
If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.