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COL2A1 Int
Entry ID: BMB30526
Int — Basement membrane interaction. See the BM Ligands tab.

Link to hereGene

Species
Human (Homo sapiens)
Gene Symbol
COL2A1
Gene Size (Bases)
33246

Link to hereProtein

Protein Name
Collagen Type II Alpha 1 Chain
Protein Classification
Collagen
Protein Molecular Weight (kD)
142
Protein Domains
IPR000885:Fibrillar collagen, C-terminal domain, IPR001007:VWFC domain
This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species
Zebrafish (Danio rerio) — 1 ortholog(s) of COL2A1
Mouse (Mus musculus) — 1 ortholog(s) of COL2A1

Link to hereProtein Localisation

Localisation Images (0)
Localisation Evidence (0)

Link to hereOther Information

Proteomics
Proteomics
BM Substrates (0)
This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.
BM Ligands (40)
Gene
ADAMTS2
ADAMTS3
ADAMTS5
ADAMTS14
COL4A1
COL4A2
COL4A3
COL4A4
COL4A5
COL4A6
COL5A1
COL6A1
COL6A2
COL6A3
COL7A1
COL8A1
COL8A2
COL9A1
COL9A2
COL9A3
COL15A1
COL17A1
COL18A1
COL28A1
MATN1
P3H1
P3H2
SPARC
TGFB1
TLL1
CD44
COL13A1
ITGA1
ITGA2
ITGA2B
ITGA10
ITGAV
ITGB1
ITGB3
SDC1
This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .
Associated Diseases (16)
Spondylometaphyseal dysplasia, corner fracture type HPO
Achondrogenesis, Type Ii OMIM
Spondyloperipheral Dysplasia OMIM
Spondyloepimetaphyseal Dysplasia, Strudwick Type OMIM
Stickler Syndrome, Type I, Nonsyndromic Ocular OMIM
Kniest Dysplasia OMIM
Spondyloepiphyseal Dysplasia Congenita OMIM
Czech Dysplasia, Metatarsal Type OMIM
Platyspondylic Lethal Skeletal Dysplasia, Torrance Type OMIM
Epiphyseal dysplasia, multiple, with myopia and deafness OMIM
Spondyloepiphyseal Dysplasia, Stanescu Type OMIM
Osteoarthritis With Mild Chondrodysplasia; OMIM
Legg-calve-perthes Disease OMIM
Stickler Syndrome, Type I OMIM
Avascular Necrosis Of Femoral Head, Primary, 1 OMIM
Spondylometaphyseal dysplasia, corner fracture type OMIM
This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References
Entrez/1280 UniProtKB/P02458
If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.