CST3 (Cystatin C) in Human (Homo sapiens) - bmBASE - A resource for basement membrane research

CST3 Int

Entry ID: BMB30612

Int — Basement membrane interaction. See the BM Ligands tab.

Gene

Link to hereGene

Species

Human (Homo sapiens)

Gene Symbol

CST3

Gene Size (Bases)

11768

Link to hereProtein

Protein Name

Cystatin C

Protein Classification

ECM regulator

Protein Molecular Weight (kD)

Protein Domains

IPR000010:Cystatin domain

This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species

Caenorhabditis elegans — 2 ortholog(s) of CST3

Zebrafish (Danio rerio) — 1 ortholog(s) of CST3

Drosophila — 2 ortholog(s) of CST3

Mouse (Mus musculus) — 1 ortholog(s) of CST3

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (1)

Pathological changes in basement membranes and dermal connective tissue of skin from patients with hereditary cystatin C amyloid angiopathy. PubMed

Found in: Human (Homo sapiens)

Reagents: Rabbit pAb for Cytostatin C (Sigma, HPA013143)

Link to hereOther Information

Proteomics

BM Substrates (0)

This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.

BM Ligands (19)

Gene
AMELX
AMTN
CTSB
CTSD
FBN1
FN1
HSPG2
LAMB1
LAMB2
LAMC1
SPARCL1
TIMP1
TIMP2
TNC
VCAN
VWA1
ADAM10
EVA1A
GPC3

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

Associated Diseases (2)

Macular degeneration, age-related, 11 HPO

Amyloidosis Vi HPO

This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References

Entrez/1471 UniProtKB/P01034

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.