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pat-3 TagInt
Entry ID: BMB31210
Tag — Tagged gene or ortholog (via endogenous labelling). See the Protein Localisation tab.
Int — Basement membrane interaction. See the BM Ligands tab.

Link to hereGene

Species
Caenorhabditis elegans
Gene Symbol
pat-3
Gene Size (Bases)
5219

Link to hereProtein

Protein Name
PAT-3
Protein Classification
Other
Protein Molecular Weight (kD)
90
Protein Domains
IPR012896:Integrin beta subunit, tail domain, IPR013111:EGF-like domain, extracellular domain, IPR014836:Integrin beta subunit, cytoplasmic domain, IPR033760:Integrin beta N-terminal domain, IPR002369:Integrin beta subunit, VWA domain
This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species
Zebrafish (Danio rerio) — 8 ortholog(s) of pat-3
Drosophila — 1 ortholog(s) of pat-3
Human (Homo sapiens) — 6 ortholog(s) of pat-3 Tag
Mouse (Mus musculus) — 6 ortholog(s) of pat-3

Link to hereProtein Localisation

Localisation Images (3)

pat-3 CRISPR knock-in information

PAT-3::mNG in embryo

PAT-3::mNG in L1 pharynx
Localisation Evidence (2)

Link to hereOther Information

Proteomics
BM Substrates (0)
This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.
BM Ligands (12)
Gene
let-2
emb-9
cle-1
unc-52
epi-1
lam-3
lam-1
lam-2
sup-17
unc-40
pat-2
ina-1
This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .
Associated Diseases (4)
Bleeding disorder, platelet-type, 16 OMIM
Glanzmann thrombasthenia OMIM
Leukocyte Adhesion Deficiency, Type I OMIM
Amelogenesis imperfecta, Type Ih OMIM
This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References
UniProtKB/Q27874 CGC Strains/NK2436
If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.