University of Manchester Logo basement membraneBASE bmBASE
FN1 Int
Entry ID: BMB30704
Int — Basement membrane interaction. See the BM Ligands tab.

Link to hereGene

Species
Human (Homo sapiens)
Gene Symbol
FN1
Gene Size (Bases)
75728

Link to hereProtein

Protein Name
Fibronectin 1
Protein Classification
ECM glycoprotein
Protein Molecular Weight (kD)
272
Protein Domains
IPR003961:Fibronectin type III domain, IPR000083:Fibronectin, type I domain, IPR000562:Fibronectin type II domain
This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species
Zebrafish (Danio rerio) — 2 ortholog(s) of FN1
Mouse (Mus musculus) — 1 ortholog(s) of FN1

Link to hereProtein Localisation

Localisation Images (0)
Localisation Evidence (0)

Link to hereOther Information

Proteomics
BM Substrates (0)
This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.
BM Ligands (50)
Gene
AMELX
AMTN
COL4A1
COL4A2
COL5A1
COL6A2
CST3
FBLN1
FBLN2
FBN1
HSPG2
ISLR
LAMB1
LAMB2
LAMC1
MMP1
MMP7
NID1
POSTN
SPARC
SPARCL1
TGFB2
TGFB1
TGFBI
THBS1
TIMP1
TIMP2
TNC
VCAN
VTN
VWA1
ADAM10
CD44
EVA1A
GPC3
ITGA2
ITGA2B
ITGA3
ITGA4
ITGA9
ITGA5
ITGA8
ITGAV
ITGB1
SDC4
ITGB3
ITGB6
ITGB7
SDC1
MMP14
This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .
Associated Diseases (2)
Glomerulopathy with fibronectin deposits 2 HPO
Spondylometaphyseal dysplasia, corner fracture type HPO
This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References
Entrez/2335 UniProtKB/P02751
If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.