LAMA4 (Laminin Subunit Alpha 4) in Human (Homo sapiens) - bmBASE - A resource for basement membrane research

IPR000742:EGF-like domain, IPR001791:Laminin G domain, IPR002049:Laminin EGF domain, IPR009254:Laminin alpha, domain I domain, IPR010307:Laminin domain II domain

This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species

Caenorhabditis elegans — 2 ortholog(s) of LAMA4 Tag

Zebrafish (Danio rerio) — 1 ortholog(s) of LAMA4

Drosophila — 1 ortholog(s) of LAMA4

Mouse (Mus musculus) — 1 ortholog(s) of LAMA4

Link to hereProtein Localisation

Localisation Images (0)

Localisation Evidence (2)

Biologically relevant laminin as chemically defined and fully human platform for human epidermal keratinocyte culture. PubMed

Found in: Human (Homo sapiens)

Reagents: Abnova MAB7869

Comment: See Figure 1
Compositional differences between infant and adult human corneal basement membranes. PubMed

Found in: Human (Homo sapiens)

Reagents: rb pAb (377; 1100+(LG4-5); 1101+(LG4-5); C0877), ms mAb FC10

Comment: See Figure 5

Link to hereOther Information

Proteomics

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices. PubMed

BM Substrates (0)

This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.

BM Ligands (32)

Gene
AGRN
HSPG2
LAMA1
LAMA2
LAMA3
LAMA5
LAMB1
LAMB2
LAMB3
LAMC1
LAMC2
LAMC3
NID1
NID2
NTN4
DAG1
ITGA1
ITGA2
ITGA3
ITGA4
ITGA6
ITGA5
ITGA8
ITGA7
ITGAV
ITGB1
RPSA
ITGB3
ITGB4
ITGB5
ITGB6
ITGB8

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

Associated Diseases (1)

Cardiomyopathy, dilated, 1jj HPO

This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References

Entrez/3910 UniProtKB/Q16363

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.