ITGB1 (Integrin subunit beta 1) in Human (Homo sapiens) - bmBASE - A resource for basement membrane research

IPR016201:PSI domain, IPR012896:Integrin beta subunit, tail domain, IPR013111:EGF-like domain, extracellular domain, IPR014836:Integrin beta subunit, cytoplasmic domain, IPR033760:Integrin beta N-terminal domain, IPR040622:Integrin beta, epidermal growth factor-like 1 domain, IPR002369:Integrin beta subunit, VWA domain

This list has been manually curated and may not be the most up to date. Further updates may be available on InterPro .

Link to hereOrthology

Orthologs by Species

Caenorhabditis elegans — 1 ortholog(s) of ITGB1 Tag

Zebrafish (Danio rerio) — 2 ortholog(s) of ITGB1

Drosophila — 1 ortholog(s) of ITGB1

Mouse (Mus musculus) — 1 ortholog(s) of ITGB1

Link to hereProtein Localisation

Localisation Images (1)

C. elegans - pat-3 L1 pharynx crop

Localisation Evidence (4)

Appearance and distribution of laminin A chain isoforms and integrin alpha 2, alpha 3, alpha 6, beta 1, and beta 4 subunits in the developing human small intestinal mucosa PubMed

Found in: Human (Homo sapiens)

Reagents: Anti-Integrin beta1 (CD29) [mAb13] (Sigma-Aldrich #MABT821)

Comment: See Fig. 2
Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes PubMed

Found in: Human (Homo sapiens)

Reagents: mouse mAb anti-Integrin α3β1 (Millipore, #MAB1992)

Comment: See Fig. 3
Basement membrane formation and re-distribution of the beta 1 integrins in a human intestinal co-culture system PubMed

Found in: Human (Homo sapiens)

Reagents: Anti-Integrin beta1 (CD29) [mAb13] (Sigma-Aldrich #MABT821)

Comment: See Fig. 5
Autologous transplantation of oral mucosal epithelial cell sheets cultured on an amniotic membrane substrate for intraoral mucosal defects PubMed

Found in: Human (Homo sapiens)

Reagents: α-Itgβ1 mAb (Chemicon, MAB1959Z)

Comment: See Fig. 2

Link to hereOther Information

Proteomics

BM Substrates (0)

This list has been manually curated and may not be the most up to date. Further updates may be available on BRENDA.

BM Ligands (42)

Gene
AGRN
COL2A1
COL4A1
COL4A2
COL4A3
COL4A4
COL4A5
COL4A6
COL5A1
COL6A1
COL6A2
COL6A3
COL7A1
COL9A1
COL9A2
COL9A3
COL18A1
FBN1
FBN2
FBN3
FN1
HSPG2
LAMA1
LAMA2
LAMA3
LAMA4
LAMA5
LAMB1
LAMB2
LAMB3
LAMC1
LAMC2
LAMC3
LUM
NID1
NPNT
TGFB1
TGFBI
THBS1
THBS2
TNC
VTN

This list has been manually curated and may not be the most up to date. Further updates may be available on STRING .

Associated Diseases (0)

This list has been manually curated and may not be the most up to date. Further updates may be available on OMIM and HPO .

Link to hereSee also

External References

Entrez/3688 UniProtKB/P05556

If an 'External Reference' link is broken, please contact the bmbase team directly at - bmbase@manchester.ac.uk.